About Compounding Medications
As one of the most experienced and comprehensive compounding centers in the U.S., we are proud to work with practitioners and patients Nationwide!
In 1938, when the Food, Drug and Cosmetic Act was passed, very few dosage forms were available and pharmacists compounded more than 250 million prescriptions annually. Nearly all of those prescriptions were compounded from bulk materials. Through the years, technical advancements in compounding equipment have allowed pharmacists to meet the growing needs of patients.
Today, a custom compound is prepared from pure, pharmaceutical-grade raw materials in accordance with a physician’s prescription, based on an individual patient’s needs. The basis of the compounding profession of pharmacy has always been the “triad,” the patient-physician-pharmacist relationship. Through this relationship, patient needs are determined by a physician, who chooses a treatment regimen that may include a compounded medication. All ingredients of compounds meet strict guidelines to ensure safety and purity.
Custom compounding prescriptions requires a trained staff of pharmacists and technicians to prepare compounded medications to strict standards, the right equipment, and specialized processes and facilities.
Did you know that 30 to 40 million prescriptions are custom compounded each year? Why? Because each patient’s health and wellness needs are different, and sometimes the medication that’s available off the shelf won’t do.
Some reasons you might need a custom-compounded medication:
- The medication you need for your condition is discontinued.
- You are allergic to a preservative, dye or binder that’s part of the medication you need.
- You need a tailored dosage strength of a medication (for example, infants need lower dosages).
- You can’t take the medication you need in the form in which it’s readily available (e.g., pills are difficult to swallow).
- You need to change the flavor of the medication you require so that you, or your child or loved one, can take it.
- You need a new treatment when other readily available ones have failed.
- Your pet needs a medication that must be compounded.
If you feel you could benefit from a custom compounded prescription, College Pharmacy is here to help answer your questions. We will work with your healthcare practitioner to find a solution to your health and wellness needs.
What is a Custom Compounded Medication?
A customized medication prepared by a pharmacist according to a doctor’s specifications to meet an individual patient’s need. Pharmacists make medications from scratch using raw materials, powders and devices.
Preservative-Free and Allergy-Free Formulations
We are able to compound medications without the excipients and preservatives found in most commercial preparations. Suitable replacements free of color, starch, yeast, sugar and preservatives are easily formulated.
Hundreds of medicines are voluntarily withdrawn from the marketplace each year. A needed treatment may not be available due to a small market share or lack of profitability. A compounded replacement may be possible.
A tablet or capsule may need to be converted into a liquid, suppository, cream, or gel form. The exact dosage, or the ideal dosage a patient needs, may not be commercially available. Compounding can provide any dosage form the patient needs.
Medicines Not Commercially Available
Many formulations will never be commercially developed due to difficulty in obtaining patents and lack of market demand. Compounding allows for medical treatments that otherwise may not be possible.
College Pharmacy: BHRT Compounding Specialists
College Pharmacy’s comprehensive custom compounding experience and state-of-the-art facility allows us to compound both traditional and advanced dosage forms. College Pharmacy’s compounding practices are both USP 795 and 797 compliant, and our testing protocol includes Potency, Sterility, Endotoxin and Fungal testing. Our Class 100 clean room enables us to produce the highest quality formulations that are potent, stable and sterile.
One of the advantages of using College Pharmacy to fill your prescription needs is the variety of dosage forms available. While traditional oral routes of administration are available, advanced dosage forms may increase compliance and treatment efficacy. The list below includes a sample of some of the dosage forms that College Pharmacy compounds.
(Specialty Dosage Form) Fused Pellet Implants
Inserted subcutaneously every 3 to 5 months. This route provides very constant hormone levels. Pellet implant formulations include: Estradiol, Testosterone, Biest, Pregnenolone, Progesterone, DHEA, Testosterone/Anastrozole.
(Specialty Dosage Form) Lipid Matrix Sublingual Tablets
Sublingual tablets are conveniently placed under the tongue for sublingual absorption and are not subject to first-pass metabolism by the liver.
(Specialty Dosage Form) Per-Q Gel™
The skin acts as a reservoir, slowly releasing hormones from its microcirculation into the main circulation continuously over a 24-hour period. This gel is extremely hypoallergenic and compliance is very good due to its common once-a-day dosing.
Traditional Dosage Forms Include
PLO Gel, Thick Gel, Topical Creams, Oral Capsules, Oil-Filled Capsules, Vaginal Suppositories, Vaginal Creams and Ointments, Injectables.
Combination Dosing of Hormones
Hormones compounded into a gel, cream, sublingual tablet, or capsule can be combined into a convenient single-dose prescription.
Gels are available in an airless metered pump bottle or an adapt-a-cap bottle and syringe. Creams are available in the Topi-Click™ Dispenser, jars, and pre-filled syringes.